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Scenario 1: Over-representation analysis

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Upload gene lists, or gene expression data to find key transcriptional regulators whose set of target genes have a significant overlap with differentially expressed genes.

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Scenario 2: REGGAE, RIF1 or RIF2 analyis

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Upload a gene expression matrix to find influential regulators, that might explain gene expression differences between two groups of samples, based on our regulator-target interaction (RTI) database.

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Scenario 3: TEPIC analysis

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Upload open-chromatin regions or histone marks to calculate affinity scores of transcription factors and all potential target genes based on position weight matrices (PWM).

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Scenario 4: INVOKE analysis

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Upload open-chromatin regions as well as gene expression data to calculate affinity scores of transcription factors and to infer the influence on their target genes using linear regression.

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